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KALVISTA PHARMACEUTICALS INC

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To the Shareholders of KALVISTA PHARMACEUTICALS INC,

The 2019 Annual Meeting of Shareholders of KALVISTA PHARMACEUTICALS INC will be held on October 02, 2019 for Shareholders of record as of August 16, 2019.

Your vote is important, so please vote at your earliest convenience.

If you are a registered holder, to vote your proxy you will need your account's unique 11-digit Control Number, which is located in your proxy e-mail or located beneath the company and account number on the upper-right side of your proxy material.

To vote online, please click Vote Your Online Proxy.

To vote by telephone, call toll - free 1 - 800 - PROXIES (1 - 800 - 776 - 9437) in the United States or 1 - 718 - 921 - 8500 from foreign countries and follow the instructions.

If you own shares through a broker, please follow the instructions that were provided to you by your broker/financial institution.

If you have any questions, please contact AST.

Thank You,

American Stock Transfer & Trust Company, LLC

Transfer Agent for KALVISTA PHARMACEUTICALS INC